Books by Gunnar Seemann

Hyperinsulinemic Hypoglycemia Associated with a CaV1.2 Variant with Mixed Gain- and Loss-of-function Effects

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Slow Conduction in the Border Zones of Patchy Fibrosis Stabilizes the Drivers for Atrial Fibrillation: Insights from Multi-scale Human Atrial Modeling

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CVAR-Seg: an Automated Signal Segmentation Pipeline for Conduction Velocity and Amplitude Restitution

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Patient-specific Identification of Atrial Flutter Vulnerability - a Computational Approach to Reveal Latent Reentry Pathways

Abstract: Atypical atrial flutter (AFlut) is a reentrant arrhythmia which patients frequently develop after ablation for atrial fibrillation (AF). Ind...

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Modeling of Electrophysiology and Tension Development in the Human Heart

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Myocyte Remodeling Due to Fibro-fatty Infiltrations Influences Arrhythmogenicity

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Electro-mechanical Whole-heart Digital Twins: a Fully Coupled Multi-physics Approach

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Spatial Patterns of Excitation at Tissue and Whole Organ Level Due to Early Afterdepolarizations

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Nano-scale Morphology of Cardiomyocyte T-tubule/sarcoplasmic Reticulum Junctions Revealed by Ultra-rapid High-pressure Freezing and Electron Tomography

Abstract: Detailed knowledge of the ultrastructure of intracellular compartments is a prerequisite for our understanding of how cells function. In car...

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Molecular Mechanism of Autosomal Eecessive Long QT-syndrome 1 Without Deafness

Abstract: KCNQ1 encodes the voltage-gated potassium (Kv) channel KCNQ1, also known as KvLQT1 or Kv7.1. Together with its ß-subunit KCNE1, also denote...

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Sodium Permeable and "hypersensitive" TREK-1 Channels Cause Ventricular Tachycardia

Abstract: In a patient with right ventricular outflow tract (RVOT) tachycardia, we identified a heterozygous point mutation in the selectivity filter ...

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Pharmacologic TWIK‐related Acid‐sensitive K+ Channel (TASK‐1) Potassium Channel Inhibitor A293 Facilitates Acute Cardioversion of Paroxysmal Atrial Fibrillation in a Porcine Large Animal Model

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